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November 12 Product: Intercept Pharmaceuticals Ocaliva Indication: Primary biliary cholangitis After initially delaying its decision last month, the FDA on Tuesday declined to give Intercept Pharmaceuticals Ocaliva (obeticholic acid) full approval for primary biliary cholangitis (PBC)

287,288 This binding initiates typical GPCR signaling, leading to G protein activation and increased intracellular cAMP

It is crucial for patients and healthcare providers to understand these side effects to optimize treatment outcomes